Entrez Gene ID | 80824 |
---|---|
Official Gene Symbol | DUSP16 (GeneCards) |
Full name | dual specificity phosphatase 16 |
Location | 12p13.2 |
Other ids | MIM : 607175 HGNC : HGNC:17909 Ensembl : ENSG00000111266 |
Other names | MKP7, MKP-7 |
Summary | This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010] |
Found 1 variant in this database.
Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
---|---|---|---|---|---|---|---|
832 | 80824 | DUSP16 | 12 | 12640121 | 12640121 | Human Skin Fibroblasts | HiSeq 2500 |