| Entrez Gene ID | 8320 |
|---|---|
| Official Gene Symbol | EOMES (GeneCards) |
| Full name | eomesodermin |
| Location | 3p24.1 |
| Other ids | Vega : OTTHUMG00000130570 MIM : 604615 HGNC : HGNC:3372 Ensembl : ENSG00000163508 |
| Other names | TBR2 |
| Summary | This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
Found 5 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 4684 | 8320 | EOMES | 3 | 27891009 | 27891009 | Asymptomatic | HiSeq X Ten |
| 4961 | 8320 | EOMES | 3 | 28206850 | 28206850 | Asymptomatic | HiSeq X Ten |
| 5419 | 8320 | EOMES | 3 | 27904495 | 27904495 | Asymptomatic | HiSeq X Ten |
| 5669 | 8320 | EOMES | 3 | 27847478 | 27847478 | Cockayne syndrome | HiSeq X Ten |
| 25092 | 8320 | EOMES | 3 | 28131310 | 28131310 | Asymptomatic | HiSeq X Ten Single cell Sequencing Cell cloning |