| Entrez Gene ID | 83439 |
|---|---|
| Official Gene Symbol | TCF7L1 (GeneCards) |
| Full name | transcription factor 7 like 1 |
| Location | 2p11.2 |
| Other ids | Vega : OTTHUMG00000130026 MIM : 604652 HGNC : HGNC:11640 Ensembl : ENSG00000152284 |
| Other names | TCF3, TCF-3 |
| Summary | This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010] |
Found 3 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 3647 | 83439 | TCF7L1 | 2 | 85415508 | 85415508 | Asymptomatic | HiSeq X Ten |
| 3939 | 83439 | TCF7L1 | 2 | 85483378 | 85483378 | Asymptomatic | HiSeq X Ten |
| 29664 | 83439 | TCF7L1 | 2 | 85529727 | 85529727 | Autism Spectrum Disorders | HiSeq X Ten MiSeq |