| Entrez Gene ID | 8471 |
|---|---|
| Official Gene Symbol | IRS4 (GeneCards) |
| Full name | insulin receptor substrate 4 |
| Location | Xq22.3 |
| Other ids | Vega : OTTHUMG00000022181 MIM : 300904 HGNC : HGNC:6128 Ensembl : ENSG00000133124 |
| Other names | IRS-4, PY160 |
| Summary | IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008] |
Found 1 variant in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 29284 | 8471 | IRS4 | X | 107977583 | 107977583 | Autism Spectrum Disorders | PASM |