PPFIA2 (Entrez ID: 8499)

Entrez Gene ID 8499
Official Gene Symbol PPFIA2 (GeneCards)
Full name PTPRF interacting protein alpha 2
Location 12q21.31
Other ids Vega : OTTHUMG00000170181
MIM : 603143
HGNC : HGNC:9246
Ensembl : ENSG00000139220
Other names None
Summary The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Variants

Found 6 variants in this database.