Entrez Gene ID | 8529 |
---|---|
Official Gene Symbol | CYP4F2 (GeneCards) |
Full name | cytochrome P450 family 4 subfamily F member 2 |
Location | 19p13.12 |
Other ids | Vega : OTTHUMG00000185995 MIM : 604426 HGNC : HGNC:2645 Ensembl : ENSG00000186115 |
Other names | CPF2 |
Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away. [provided by RefSeq, Jul 2008] |
Found 3 variants in this database.
Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
---|---|---|---|---|---|---|---|
20827 | 8529 | CYP4F2 | 19 | 16008276 | 16008276 | Asymptomatic | HiSeq 2000 |
20880 | 8529 | CYP4F2 | 19 | 15996142 | 15996142 | Asymptomatic | HiSeq 2000 HiSeq X Ten |
21086 | 8529 | CYP4F2 | 19 | 16019228 | 16019228 | Xeroderma Pigmentosum | HiSeq 2000 HiSeq X Ten |