| Entrez Gene ID | 8850 |
|---|---|
| Official Gene Symbol | KAT2B (GeneCards) |
| Full name | lysine acetyltransferase 2B |
| Location | 3p24.3 |
| Other ids | Vega : OTTHUMG00000130481 MIM : 602303 HGNC : HGNC:8638 Ensembl : ENSG00000114166 |
| Other names | CAF, PCAF, P/CAF |
| Summary | CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008] |
Found 4 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 1399 | 8850 | KAT2B | 3 | 20161090 | 20161090 | Autism Spectrum Disorders | NextSeq500 v2 |
| 5773 | 8850 | KAT2B | 3 | 20150629 | 20150629 | Cockayne syndrome | NextSeq500 v2 HiSeq X Ten |
| 29110 | 8850 | KAT2B | 3 | 20161089 | 20161089 | Autism Spectrum Disorders | NextSeq500 v2 HiSeq X Ten HiSeq Pyrosequencing |
| 29371 | 8850 | KAT2B | 3 | 20161089 | 20161089 | Autism Spectrum Disorders | NextSeq500 v2 HiSeq X Ten HiSeq Pyrosequencing MiSeq |