| Entrez Gene ID | 8905 |
|---|---|
| Official Gene Symbol | AP1S2 (GeneCards) |
| Full name | adaptor related protein complex 1 subunit sigma 2 |
| Location | Xp22.2 |
| Other ids | Vega : OTTHUMG00000021186 MIM : 300629 HGNC : HGNC:560 Ensembl : ENSG00000182287 |
| Other names | PGS, DC22, MRX59, MRXS5, MRXSF, MRXS21, SIGMA1B |
| Summary | Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013] |