Other names |
NK4,
TAIF,
TAIFa,
TAIFb,
TAIFc,
TAIFd,
IL-32beta,
IL-32alpha,
IL-32delta,
IL-32gamma
|
Summary |
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |