RGS6 (Entrez ID: 9628)

Entrez Gene ID 9628
Official Gene Symbol RGS6 (GeneCards)
Full name regulator of G protein signaling 6
Location 14q24.2
Other ids Vega : OTTHUMG00000171340
MIM : 603894
HGNC : HGNC:10002
Ensembl : ENSG00000182732
Other names GAP, S914, HA117
Summary This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]

Variants

Found 8 variants in this database.