| Entrez Gene ID |
6595 (NCBI Gene) |
| Official Gene Symbol |
SMARCA2 (GeneCards) |
| Number of variants in SMARCA2 in this database |
8 (view all the variants) |
| Full name |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| Band |
9p24.3 |
| Other IDs |
Vega:
OTTHUMG00000019445
OMIM:
600014
HGNC:
HGNC:11098
Ensembl:
ENSG00000080503
|
| Other names |
BRM,
SNF2,
SWI2,
hBRM,
NCBRS,
Sth1p,
BAF190,
SNF2L2,
SNF2LA,
hSNF2a
|
| Summary |
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014] |