| Entrez Gene ID |
2042 (NCBI Gene) |
| Official Gene Symbol |
EPHA3 (GeneCards) |
| Number of variants in EPHA3 in this database |
13 (view all the variants) |
| Full name |
EPH receptor A3 |
| Band |
3p11.1 |
| Other IDs |
Vega:
OTTHUMG00000159040
OMIM:
179611
HGNC:
HGNC:3387
Ensembl:
ENSG00000044524
|
| Other names |
EK4,
ETK,
HEK,
ETK1,
HEK4,
TYRO4
|
| Summary |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] |