| Entrez Gene ID |
1268 (NCBI Gene) |
| Official Gene Symbol |
CNR1 (GeneCards) |
| Number of variants in CNR1 in this database |
6 (view all the variants) |
| Full name |
cannabinoid receptor 1 |
| Band |
6q15 |
| Other IDs |
Vega:
OTTHUMG00000015184
OMIM:
114610
HGNC:
HGNC:2159
Ensembl:
ENSG00000118432
|
| Other names |
CB1,
CNR,
CB-R,
CB1A,
CB1R,
CANN6,
CB1K5
|
| Summary |
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009] |