| Entrez Gene ID |
23414 (NCBI Gene) |
| Official Gene Symbol |
ZFPM2 (GeneCards) |
| Number of variants in ZFPM2 in this database |
6 (view all the variants) |
| Full name |
zinc finger protein, FOG family member 2 |
| Band |
8q23.1 |
| Other IDs |
Vega:
OTTHUMG00000164818
OMIM:
603693
HGNC:
HGNC:16700
Ensembl:
ENSG00000169946
|
| Other names |
DIH3,
FOG2,
SRXY9,
ZNF89B,
hFOG-2,
ZC2HC11B
|
| Summary |
The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008] |