| Entrez Gene ID |
1778 (NCBI Gene) |
| Official Gene Symbol |
DYNC1H1 (GeneCards) |
| Number of variants in DYNC1H1 in this database |
6 (view all the variants) |
| Full name |
dynein cytoplasmic 1 heavy chain 1 |
| Band |
14q32.31 |
| Other IDs |
Vega:
OTTHUMG00000171644
OMIM:
600112
HGNC:
HGNC:2961
Ensembl:
ENSG00000197102
|
| Other names |
p22,
DHC1,
DNCL,
DYHC,
HL-3,
CMT2O,
DHC1a,
DNCH1,
DNECL,
Dnchc1,
SMALED1
|
| Summary |
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008] |