| Entrez Gene ID |
2897 (NCBI Gene) |
| Official Gene Symbol |
GRIK1 (GeneCards) |
| Number of variants in GRIK1 in this database |
7 (view all the variants) |
| Full name |
glutamate ionotropic receptor kainate type subunit 1 |
| Band |
21q21.3 |
| Other IDs |
Vega:
OTTHUMG00000078879
OMIM:
138245
HGNC:
HGNC:4579
Ensembl:
ENSG00000171189
|
| Other names |
EAA3,
EEA3,
GLR5,
GLUR5,
GlK1,
glR-5
|
| Summary |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008] |