| Entrez Gene ID |
7307 (NCBI Gene) |
| Official Gene Symbol |
U2AF1 (GeneCards) |
| Number of variants in U2AF1 in this database |
3 (view all the variants) |
| Full name |
U2 small nuclear RNA auxiliary factor 1 |
| Band |
21q22.3 |
| Other IDs |
Vega:
OTTHUMG00000086836
OMIM:
191317
HGNC:
HGNC:12453
Ensembl:
ENSG00000160201
|
| Other names |
RN,
FP793,
U2AF35,
U2AFBP,
RNU2AF1
|
| Summary |
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |