| Entrez Gene ID |
3096 (NCBI Gene) |
| Official Gene Symbol |
HIVEP1 (GeneCards) |
| Number of variants in HIVEP1 in this database |
6 (view all the variants) |
| Full name |
human immunodeficiency virus type I enhancer binding protein 1 |
| Band |
6p24.1 |
| Other IDs |
Vega:
OTTHUMG00000014265
OMIM:
194540
HGNC:
HGNC:4920
Ensembl:
ENSG00000095951
|
| Other names |
GAAP,
ZAS1,
CIRIP,
MBP-1,
ZNF40,
CRYBP1,
ZNF40A,
PRDII-BF1,
Schnrri-1
|
| Summary |
This gene encodes a transcription factor belonging to the ZAS family, members of which are large proteins that contain a ZAS domain - a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specifically to the DNA sequence motif, GGGACTTTCC, found in the enhancer elements of several viral promoters, including human immunodeficiency virus (HIV), and to related sequences found in the enhancer elements of a number of cellular promoters. This protein binds to this sequence motif, suggesting a role in the transcriptional regulation of both viral and cellular genes. [provided by RefSeq, Oct 2011] |