AutismKB 2.0

Annotation Details for ABI1


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Basic Information Top
Gene Symbol:ABI1 ( ABI-1,E3B1,NAP1BP,SSH3BP,SSH3BP1 )
Gene Full Name: abl-interactor 1
Band: 10p12.1
Quick LinksEntrez ID:10006; OMIM: 603050; Uniprot ID:ABI1_HUMAN; ENSEMBL ID: ENSG00000136754; HGNC ID: 11320
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IDA-intracellular17101133
GO:0005634IEA-nucleus-
GO:0005783TAS-endoplasmic reticulum9593709
GO:0005829TAS-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0014069IEA-postsynaptic density-
GO:0030027IDA-lamellipodium11516653
GO:0030054IEA-cell junction-
GO:0030175IDA-filopodium11516653
GO:0030426IEA-growth cone-
GO:0031209IDA-SCAR complex21107423
GO:0045211IEA-postsynaptic membrane-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding9010225
GO:0008092TAS-cytoskeletal protein binding9593709
GO:0017124IPI-SH3 domain binding19798448
GO:0030296IEA-protein tyrosine kinase activator activity-
GO:0032403IDA-protein complex binding18560548
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0001756IEA-somitogenesis-
GO:0006928IDA-movement of cell or subcellular component11516653
GO:0007169TAS-transmembrane receptor protein tyrosine kinase signaling pathway9010225
GO:0008154NAS-actin polymerization or depolymerization11516653
GO:0008285TAS-negative regulation of cell proliferation9010225
GO:0016032IEA-viral process-
GO:0018108IDA-peptidyl-tyrosine phosphorylation17101133
GO:0035855IEA-megakaryocyte development-
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:0048813IEA-dendrite morphogenesis-
GO:0061098IEA-positive regulation of protein tyrosine kinase activity-
GO:0072673IEA-lamellipodium morphogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ABI1ABL11065439010225 11418237 12672821 Affinity Capture-Western; Reconstituted Complex
ABI1ABL11153249010225 11418237 12672821 Affinity Capture-Western; Reconstituted Complex
ABI1APBB111532416055720 Affinity Capture-MS
ABI1APBB110681916055720 Affinity Capture-MS
ABI1EPS81083739010225 11099046 14565974 Affinity Capture-Western; Reconstituted Complex
ABI1EPS81153249010225 11099046 14565974 Affinity Capture-Western; Reconstituted Complex
ABI1NCK111077011418237 Reconstituted Complex
ABI1NCK111532411418237 Reconstituted Complex
ABI1SOS111253710499589 Affinity Capture-Western; Reconstituted Complex
ABI1SOS111532410499589 Affinity Capture-Western; Reconstituted Complex
ABI1GAS711409416055720 Affinity Capture-MS
ABI1GAS711532416055720 Affinity Capture-MS
NCKAP1ABI111532411418237 Affinity Capture-Western; Two-hybrid
NCKAP1ABI111600311418237 Affinity Capture-Western; Two-hybrid
ENAHABI112085812672821 Reconstituted Complex; Two-hybrid
ENAHABI111532412672821 Reconstituted Complex; Two-hybrid
EPS8L1ABI112021814565974 Affinity Capture-Western
EPS8L1ABI111532414565974 Affinity Capture-Western
EPS8L2ABI112229714565974 Affinity Capture-Western
EPS8L2ABI111532414565974 Affinity Capture-Western
EPS8L3ABI112272114565974 Affinity Capture-Western
EPS8L3ABI111532414565974 Affinity Capture-Western
TCERG1ABI111612016055720 Affinity Capture-MS
TCERG1ABI111532416055720 Affinity Capture-MS
PRPF40AABI111532416055720 Affinity Capture-MS
PRPF40AABI112079216055720 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
ABI1ABL119470111418237 hNap1BP interacts with Abl.
ABI1DNM221652015696170 An unspecified isoform of Dyn2 interacts with Abi-1. This interaction was modeled on a demonstrated interaction between human Dyn2 and Abi-1 from an unspecified species.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104913
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1701'