AutismKB 2.0

Annotation Details for KCNE3


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Basic Information Top
Gene Symbol:KCNE3 ( DKFZp781H21101,HOKPP,HYPP,MGC102685,MGC129924,MiRP2 )
Gene Full Name: potassium voltage-gated channel, Isk-related family, member 3
Band: 11q13.4
Quick LinksEntrez ID:10008; OMIM: 604433; Uniprot ID:KCNE3_HUMAN; ENSEMBL ID: ENSG00000175538; HGNC ID: 6243
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm12954870
GO:0005886IPIcolocalizes_withplasma membrane10646604
GO:0008076IDAcolocalizes_withvoltage-gated potassium channel complex12954870
GO:0030425IDA-dendrite12954870
GO:0031982IDA-vesicle10646604
GO:0032809IDA-neuronal cell body membrane12954870
GO:0043204IDA-perikaryon12954870
GO:0045121IDA-membrane raft20533308
GO ID Evidence Qualifier GO_term References
GO:0005249IEA-voltage-gated potassium channel activity-
GO:0005515IPI-protein binding20533308
GO:0015459IDA-potassium channel regulator activity12954870
GO:0044325IEA-ion channel binding-
GO ID Evidence Qualifier GO_term References
GO:0071805IEA-potassium ion transmembrane transport-
GO:0086091IMP-regulation of heart rate by cardiac conduction22987075
GO:1901387IEA-positive regulation of voltage-gated calcium channel activity-
GO:1902260IDA-negative regulation of delayed rectifier potassium channel activity12954870
GO:1903765IDA-negative regulation of potassium ion export across plasma membrane22987075
GO:1903817IDA-negative regulation of voltage-gated potassium channel activity22987075
GO:1905025IMP-negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential22987075
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1891124
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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