AutismKB 2.0

Annotation Details for CDH3


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Basic Information Top
Gene Symbol:CDH3 ( CDHP,HJMD,PCAD )
Gene Full Name: cadherin 3, type 1, P-cadherin (placental)
Band: 16q22.1
Quick LinksEntrez ID:1001; OMIM: 114021; Uniprot ID:CADH3_HUMAN; ENSEMBL ID: ENSG00000062038; HGNC ID: 1762
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IEA-cytoplasm-
GO:0005886IDA-plasma membrane10460003
GO:0005886TAS-plasma membrane-
GO:0005913IEA-cell-cell adherens junction-
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0003674ND-molecular_function-
GO:0005509IEA-calcium ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001895IMP-retina homeostasis23143461
GO:0007155TAS-cell adhesion2793940
GO:0007156IEA-homophilic cell adhesion via plasma membrane adhesion molecules-
GO:0007601IEA-visual perception-
GO:0010628IMP-positive regulation of gene expression23334344
GO:0010838IMP-positive regulation of keratinocyte proliferation22696062
GO:0016337IEA-single organismal cell-cell adhesion-
GO:0022405IMP-hair cycle process23143461
GO:0031424IMP-keratinization22696062
GO:0032773IMP-positive regulation of monophenol monooxygenase activity23334344
GO:0032912IMP-negative regulation of transforming growth factor beta2 production22696062
GO:0034332TAS-adherens junction organization-
GO:0042060IEA-wound healing-
GO:0042493IEA-response to drug-
GO:0043568IMP-positive regulation of insulin-like growth factor receptor signaling pathway22696062
GO:0048023IMP-positive regulation of melanin biosynthetic process23334344
GO:0051796IMP-negative regulation of timing of catagen22696062
GO:0060070IMP-canonical Wnt signaling pathway23334344
GO:0060901IMP-regulation of hair cycle by canonical Wnt signaling pathway22696062
GO:1902910IMP-positive regulation of melanosome transport23334344
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CDH3CDH110743610910767 Affinity Capture-Western; Co-purification
CDH3CDH110743410910767 Affinity Capture-Western; Co-purification
CTNND1CDH31074368660921 Affinity Capture-Western
CTNND1CDH31078818660921 Affinity Capture-Western
CTNNA1CDH310743610381631 10910767 Affinity Capture-Western; Co-purification
CTNNA1CDH310787610381631 10910767 Affinity Capture-Western; Co-purification
CTNNB1CDH310743610381631 10910767 Affinity Capture-Western; Co-purification
CTNNB1CDH310788010381631 10910767 Affinity Capture-Western; Co-purification
CDH3CDH310743610910767 Affinity Capture-Western; Co-purification
JUPCDH310993110910767 Affinity Capture-Western; Co-purification
JUPCDH310743610910767 Affinity Capture-Western; Co-purification
CD2APCDH310743615331416 Affinity Capture-Western
CD2APCDH311714015331416 Affinity Capture-Western
NPHS1CDH311092815331416 Affinity Capture-Western; Reconstituted Complex
NPHS1CDH310743615331416 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88356
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018