AutismKB 2.0

Annotation Details for PDCD6IP


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PDCD6IP ( AIP1,Alix,DRIP4,HP95,MGC17003 )
Gene Full Name: programmed cell death 6 interacting protein
Band: 3p22.3
Quick LinksEntrez ID:10015; OMIM: 608074; Uniprot ID:PDC6I_HUMAN; ENSEMBL ID: ENSG00000170248; HGNC ID: 8766
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001772IDA-immunological synapse19706535
GO:0005815IEA-microtubule organizing center-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005923IEA-bicellular tight junction-
GO:0005925IDA-focal adhesion21423176
GO:0016020IDA-membrane19946888
GO:0042470IEA-melanosome-
GO:0042641ISS-actomyosin-
GO:0043209IEA-myelin sheath-
GO:0070062IDA-extracellular exosome15326289
GO:0070971IMP-endoplasmic reticulum exit site16957052
GO:0090543IDA-Flemming body18641129
GO:1903561IDA-extracellular vesicle24769233
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11883939
GO:0031871IPI-proteinase activated receptor binding22547407
GO:0042803IPI-protein homodimerization activity14505570
GO:0048306IPI-calcium-dependent protein binding18256029
GO ID Evidence Qualifier GO_term References
GO:0000281IDA-mitotic cytokinesis18641129
GO:0000915ISS-actomyosin contractile ring assembly-
GO:0000920IMP-cell separation after cytokinesis20616062
GO:0006915IEA-apoptotic process-
GO:0006997IMPNOTnucleus organization20616062
GO:0007080IMPNOTmitotic metaphase plate congression20616062
GO:0010824IMP-regulation of centrosome duplication20616062
GO:0015031IEA-protein transport-
GO:0019058TAS-viral life cycle-
GO:0036258NAS-multivesicular body assembly20588296
GO:0039702IGI-viral budding via host ESCRT complex24107264
GO:0039702NAS-viral budding via host ESCRT complex20588296
GO:0045199ISS-maintenance of epithelial cell apical/basal polarity-
GO:0046755IDA-viral budding18641129
GO:0051260IDA-protein homooligomerization18641129
GO:0070830ISS-bicellular tight junction assembly-
GO:0090559ISS-regulation of membrane permeability-
GO:0090611IMP-ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway22547407
GO:1901673IMPNOTregulation of mitotic spindle assembly20616062
GO:1903543IMP-positive regulation of exosomal secretion22660413
GO:1903551IMP-regulation of extracellular exosome assembly24105262
GO:1903553IMP-positive regulation of extracellular exosome assembly22660413
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PDCD6IPEGFR10827615456872 Affinity Capture-Western
PDCD6IPEGFR11533215456872 Affinity Capture-Western
PDCD6IPGRB210914220936779 Two-hybrid
PDCD6IPGRB211533220936779 Two-hybrid
PDCD6IPNEDD411533220519395 Affinity Capture-Western
PDCD6IPNEDD411081120519395 Affinity Capture-Western
PDCD6IPPDGFRB11118517082185 Affinity Capture-Western
PDCD6IPPDGFRB11533217082185 Affinity Capture-Western
PDCD6IPSH3GL211235315456872 Affinity Capture-Western
PDCD6IPSH3GL211533215456872 Affinity Capture-Western
PDCD6IPUSP711533217927229 Affinity Capture-Western
PDCD6IPUSP711362217927229 Affinity Capture-Western
PDCD6IPSTK2411533217353931 Affinity Capture-MS
PDCD6IPSTK2411401117353931 Affinity Capture-MS
PDCD6IPTTF211403612927788 Two-hybrid
PDCD6IPTTF211533212927788 Two-hybrid
PDCD6PDCD6IP1153329880530 11883939 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PDCD6PDCD6IP1153339880530 11883939 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SH3KBP1PDCD6IP11533215456872 Reconstituted Complex
SH3KBP1PDCD6IP11902915456872 Reconstituted Complex
VPS37CPDCD6IP11533215509564 Two-hybrid
VPS37CPDCD6IP12037115509564 Two-hybrid
PHLDA3PDCD6IP11533217353931 Affinity Capture-MS
PHLDA3PDCD6IP11714517353931 Affinity Capture-MS
GSTK1PDCD6IP13187517353931 Affinity Capture-MS
GSTK1PDCD6IP11533217353931 Affinity Capture-MS
UBA5PDCD6IP11533220562859 Affinity Capture-MS
UBA5PDCD6IP12296420562859 Affinity Capture-MS
MAP1LC3APDCD6IP11533220562859 Affinity Capture-MS
MAP1LC3APDCD6IP12413720562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1333753
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2678'