AutismKB 2.0

Annotation Details for CDH5


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Basic Information Top
Gene Symbol:CDH5 ( 7B4,CD144,FLJ17376 )
Gene Full Name: cadherin 5, type 2 (vascular endothelium)
Band: 16q21
Quick LinksEntrez ID:1003; OMIM: 601120; Uniprot ID:CADH5_HUMAN; ENSEMBL ID: ENSG00000179776; HGNC ID: 1764
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane25978380
GO:0005886TAS-plasma membrane-
GO:0005911IDA-cell-cell junction19996314
GO:0005913IDA-cell-cell adherens junction25978380
GO:0005923IEA-bicellular tight junction-
GO:0009897IEA-external side of plasma membrane-
GO:0009986IDA-cell surface23288152
GO:0016020TAS-membrane9219219
GO:0016021IEA-integral component of membrane-
GO:0030054ISS-cell junction-
GO ID Evidence Qualifier GO_term References
GO:0005102IPI-receptor binding12088286
GO:0005509IEA-calcium ion binding-
GO:0005515IPI-protein binding17057644
GO:0008013IPI-beta-catenin binding18287330
GO:0019903IEA-protein phosphatase binding-
GO:0044325IPI-ion channel binding19996314
GO ID Evidence Qualifier GO_term References
GO:0001955IEA-blood vessel maturation-
GO:0007043IMP-cell-cell junction assembly23288152
GO:0007156IEA-homophilic cell adhesion via plasma membrane adhesion molecules-
GO:0007179IDA-transforming growth factor beta receptor signaling pathway21168935
GO:0008285IEA-negative regulation of cell proliferation-
GO:0016337IEA-single organismal cell-cell adhesion-
GO:0034332TAS-adherens junction organization-
GO:1903142IMP-positive regulation of establishment of endothelial barrier23288152
GO:2000114IMP-regulation of establishment of cell polarity20332120
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CTNND1CDH51074389378757 11855855 Affinity Capture-Western
CTNND1CDH51078819378757 11855855 Affinity Capture-Western
CTNNA1CDH51074389434630 12003790 Affinity Capture-Western
CTNNA1CDH51078769434630 12003790 Affinity Capture-Western
CTNNB1CDH51074389434630 12003790 20224040 Affinity Capture-Western
CTNNB1CDH51078809434630 12003790 20224040 Affinity Capture-Western
JUPCDH51099319434630 12003790 Affinity Capture-Western
JUPCDH51074389434630 12003790 Affinity Capture-Western
DSPCDH51081669739078 Affinity Capture-Western
DSPCDH51074389739078 Affinity Capture-Western
PTPN11CDH511174510681592 Affinity Capture-Western
PTPN11CDH510743810681592 Affinity Capture-Western
FGACDH510743811900554 Reconstituted Complex
FGACDH510853411900554 Reconstituted Complex
KDRCDH510743811950700 Affinity Capture-Western
KDRCDH510999211950700 Affinity Capture-Western
SHC1CDH510743811950700 Affinity Capture-Western
SHC1CDH511236111950700 Affinity Capture-Western
VIMCDH510743812003790 Affinity Capture-Western
VIMCDH511327212003790 Affinity Capture-Western
P2RX4CDH511106412088286 Affinity Capture-Western
P2RX4CDH510743812088286 Affinity Capture-Western
PTPRBCDH511175112234928 Affinity Capture-Western; Biochemical Activity
PTPRBCDH510743812234928 Affinity Capture-Western; Biochemical Activity
PKP4CDH511407412426320 Two-hybrid
PKP4CDH510743812426320 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:105057
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040816-1'