AutismKB 2.0

Annotation Details for ARPC5


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Basic Information Top
Gene Symbol:ARPC5 ( ARC16,MGC88523,dJ127C7.3,p16-Arc )
Gene Full Name: actin related protein 2/3 complex, subunit 5, 16kDa
Band: 1q25.3
Quick LinksEntrez ID:10092; OMIM: 604227; Uniprot ID:ARPC5_HUMAN; ENSEMBL ID: ENSG00000162704; HGNC ID: 708
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005737TAS-cytoplasm9359840
GO:0005768IEA-endosome-
GO:0005829TAS-cytosol-
GO:0005885IDA-Arp2/3 protein complex11741539
GO:0005925IDA-focal adhesion21423176
GO:0015629TAS-actin cytoskeleton9230079
GO:0030027IEA-lamellipodium-
GO:0030426IEA-growth cone-
GO:0034774TAS-secretory granule lumen-
GO:0070062IDA-extracellular exosome19056867
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0005200IDA-structural constituent of cytoskeleton11741539
GO:0005515IPI-protein binding11162547
GO:0051015IDAcontributes_toactin filament binding11741539
GO ID Evidence Qualifier GO_term References
GO:0006928TAS-movement of cell or subcellular component9230079
GO:0014909IEA-smooth muscle cell migration-
GO:0016477IMP-cell migration22378351
GO:0021769IEA-orbitofrontal cortex development-
GO:0030011IEA-maintenance of cell polarity-
GO:0030036TAS-actin cytoskeleton organization9359840
GO:0034314IDA-Arp2/3 complex-mediated actin nucleation11741539
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0043312TAS-neutrophil degranulation-
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0051639IEA-actin filament network formation-
GO:0061024TAS-membrane organization-
GO:0061842IEA-microtubule organizing center localization-
GO:0097581IEA-lamellipodium organization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ARPC5NR3C110916510508170 Two-hybrid
ARPC5NR3C111539910508170 Two-hybrid
ARPC5EIF3H11539919615732 Affinity Capture-MS
ARPC5EIF3H11421619615732 Affinity Capture-MS
ARPC4ARPC511539911162547 12451597 Two-hybrid
ARPC4ARPC511540011162547 12451597 Two-hybrid
ACTR3BARPC511539917353931 Affinity Capture-MS
ACTR3BARPC512142917353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1915021
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-8448'