AutismKB 2.0

Annotation Details for PDIA6


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Basic Information Top
Gene Symbol:PDIA6 ( ERP5,P5,TXNDC7 )
Gene Full Name: protein disulfide isomerase family A, member 6
Band: 2p25.1
Quick LinksEntrez ID:10130; OMIM: 611099; Uniprot ID:PDIA6_HUMAN; ENSEMBL ID: ENSG00000143870; HGNC ID: 30168
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space19995400
GO:0005783IDA-endoplasmic reticulum-
GO:0005783TAS-endoplasmic reticulum16130169
GO:0005788TAS-endoplasmic reticulum lumen-
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0005793IDA-endoplasmic reticulum-Golgi intermediate compartment15308636
GO:0005829IDA-cytosol-
GO:0005886IEA-plasma membrane-
GO:0034663ISS-endoplasmic reticulum chaperone complex-
GO:0042470IEA-melanosome-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0003756IBA-protein disulfide isomerase activity-
GO:0005515IPI-protein binding15466936
GO:0015037IDA-peptide disulfide oxidoreductase activity16677074
GO ID Evidence Qualifier GO_term References
GO:0006457TAS-protein folding7590364
GO:0034976IBA-response to endoplasmic reticulum stress-
GO:0036498TAS-IRE1-mediated unfolded protein response-
GO:0043277IBA-apoptotic cell clearance-
GO:0043687TAS-post-translational protein modification-
GO:0044267TAS-cellular protein metabolic process-
GO:0045454IEA-cell redox homeostasis-
GO:0055114IEA-oxidation-reduction process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PDIA6NME211543417353931 Affinity Capture-MS
PDIA6NME211089517353931 Affinity Capture-MS
PDIA6TNFRSF1411429817353931 Affinity Capture-MS
PDIA6TNFRSF1411543417353931 Affinity Capture-MS
PDIA6IKBKE11500017353931 Affinity Capture-MS
PDIA6IKBKE11543417353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919103
  • Data Attributes: MGI curated and HomoloGene calculated
No data