AutismKB 2.0

Annotation Details for RASA4


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Basic Information Top
Gene Symbol:RASA4 ( CAPRI,FLJ59070,GAPL,KIAA0538,MGC131890,RASA4B )
Gene Full Name: RAS p21 protein activator 4
Band: 7q22.1
Quick LinksEntrez ID:10156; OMIM: 607943; Uniprot ID:RASL2_HUMAN; ENSEMBL ID: ENSG00000105808; HGNC ID: 23181
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol16009725
GO:0005829TAS-cytosol-
GO:0005886IDAcolocalizes_withplasma membrane16009725
GO:0031235IBA-intrinsic component of the cytoplasmic side of the plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005096IDA-GTPase activator activity11448776
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0034260IDA-negative regulation of GTPase activity12845332
GO:0034260IMP-negative regulation of GTPase activity11448776
GO:0043547IEA-positive regulation of GTPase activity-
GO:0046580IBA-negative regulation of Ras protein signal transduction-
GO:0071277IMP-cellular response to calcium ion16009725
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1858600
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018