AutismKB 2.0

Annotation Details for WASF2


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Basic Information Top
Gene Symbol:WASF2 ( SCAR2,WAVE2,dJ393P12.2 )
Gene Full Name: WAS protein family, member 2
Band: 1p36.11
Quick LinksEntrez ID:10163; OMIM: 605875; Uniprot ID:WASF2_HUMAN; ENSEMBL ID: ENSG00000158195; HGNC ID: 12733
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726IEA-ruffle-
GO:0005622IDA-intracellular17101133
GO:0005769IEA-early endosome-
GO:0005829TAS-cytosol-
GO:0005911IEA-cell-cell junction-
GO:0015629TAS-actin cytoskeleton10970852
GO:0030027IDA-lamellipodium17101133
GO:0031209IMP-SCAR complex21107423
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0003779IEA-actin binding-
GO:0005515IPI-protein binding11130076
GO:0017124IPI-SH3 domain binding19798448
GO:0032403IDA-protein complex binding18560548
GO:0032403IMP-protein complex binding21107423
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0001525IEA-angiogenesis-
GO:0001667IEA-ameboidal-type cell migration-
GO:0007188TAS-adenylate cyclase-modulating G-protein coupled receptor signaling pathway9732292
GO:0010592IMP-positive regulation of lamellipodium assembly18560548
GO:0016032IEA-viral process-
GO:0016601IEA-Rac protein signal transduction-
GO:0030032IEA-lamellipodium assembly-
GO:0030036IEA-actin cytoskeleton organization-
GO:0030048IEA-actin filament-based movement-
GO:0035855IEA-megakaryocyte development-
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:0051497IMP-negative regulation of stress fiber assembly21107423
GO:0072673IEA-lamellipodium morphogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
WASF2APBB111546516055720 Affinity Capture-MS
WASF2APBB110681916055720 Affinity Capture-MS
WASF2GAS711409416055720 Affinity Capture-MS
WASF2GAS711546516055720 Affinity Capture-MS
WASF2ACTR311546510381382 Reconstituted Complex
WASF2ACTR311540310381382 Reconstituted Complex
BAIAP2WASF211546511130076 Far Western; Reconstituted Complex
BAIAP2WASF211572111130076 Far Western; Reconstituted Complex
TCERG1WASF211612016055720 Affinity Capture-MS
TCERG1WASF211546516055720 Affinity Capture-MS
PRPF40AWASF211546516055720 Affinity Capture-MS
PRPF40AWASF212079216055720 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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