AutismKB 2.0

Annotation Details for SORBS3


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Basic Information Top
Gene Symbol:SORBS3 ( SCAM-1,SCAM1,SH3D4,VINEXIN )
Gene Full Name: sorbin and SH3 domain containing 3
Band: 8p21.3
Quick LinksEntrez ID:10174; OMIM: 610795; Uniprot ID:VINEX_HUMAN; ENSEMBL ID: ENSG00000120896; HGNC ID: 30907
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005829TAS-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0005925IDA-focal adhesion21423176
GO:0005925IDAcolocalizes_withfocal adhesion9885244
GO ID Evidence Qualifier GO_term References
GO:0005200TAS-structural constituent of cytoskeleton9885244
GO:0005515IPI-protein binding12660241
GO:0008134IEA-transcription factor binding-
GO:0017166IPI-vinculin binding9885244
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0006936TAS-muscle contraction-
GO:0007015IEA-actin filament organization-
GO:0007155TAS-cell adhesion9885244
GO:0031589IEA-cell-substrate adhesion-
GO:0043410IEA-positive regulation of MAPK cascade-
GO:0051495NAS-positive regulation of cytoskeleton organization9885244
GO:0051496IDA-positive regulation of stress fiber assembly9885244
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SORBS3CBLB11547516189514 Two-hybrid
SORBS3CBLB10731616189514 Two-hybrid
SORBS3DVL211547516189514 Two-hybrid
SORBS3DVL210818916189514 Two-hybrid
SORBS3HNRNPK10943116189514 Two-hybrid
SORBS3HNRNPK11547516189514 Two-hybrid
SORBS3MAPK111158015184391 Affinity Capture-Western; Biochemical Activity
SORBS3MAPK111547515184391 Affinity Capture-Western; Biochemical Activity
SORBS3ZBTB2511547516189514 Two-hybrid
SORBS3ZBTB2511342216189514 Two-hybrid
SORBS3ZBED111547516189514 Two-hybrid
SORBS3ZBED111462616189514 Two-hybrid
SORBS3DLG511466212657639 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SORBS3DLG511547512657639 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SORBS3SAFB211547512660241 Affinity Capture-Western
SORBS3SAFB211502212660241 Affinity Capture-Western
SORBS3KIAA040811547516189514 Two-hybrid
SORBS3KIAA040811507816189514 Two-hybrid
FLOT1SORBS311547511481476 Reconstituted Complex
FLOT1SORBS311550611481476 Reconstituted Complex
EFSSORBS311547516189514 Two-hybrid
EFSSORBS311556716189514 Two-hybrid
DDX17SORBS311577616189514 Two-hybrid
DDX17SORBS311547516189514 Two-hybrid
RBMXSORBS311813416189514 Two-hybrid
RBMXSORBS311547516189514 Two-hybrid
ADAMTSL4SORBS311547516189514 Two-hybrid
ADAMTSL4SORBS312000216189514 Two-hybrid
KIAA1217SORBS311547516189514 Two-hybrid
KIAA1217SORBS312111116189514 Two-hybrid
DMRTB1SORBS311547516189514 Two-hybrid
DMRTB1SORBS312201216189514 Two-hybrid
CPSF7SORBS312295716189514 Two-hybrid
CPSF7SORBS311547516189514 Two-hybrid
No data
Gene Symbol Interactant Interaction ID References Description
SORBS3INPPL10290016302969 -
SORBS3INPPL11153516302969 -
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SORBS3rs2280889 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:700013
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050327-1'