AutismKB 2.0

Annotation Details for CALCRL


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Basic Information Top
Gene Symbol:CALCRL ( CGRPR,CRLR )
Gene Full Name: calcitonin receptor-like
Band: 2q32.1
Quick LinksEntrez ID:10203; OMIM: 114190; Uniprot ID:CALRL_HUMAN; ENSEMBL ID: ENSG00000064989; HGNC ID: 16709
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005764IDA-lysosome10882736
GO:0005768IDA-endosome10882736
GO:0005783IDA-endoplasmic reticulum10882736
GO:0005886IDA-plasma membrane10882736
GO:0005886IDAcolocalizes_withplasma membrane9620797
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane7818539
GO ID Evidence Qualifier GO_term References
GO:0001605IDA-adrenomedullin receptor activity22102369
GO:0001635IEA-calcitonin gene-related peptide receptor activity-
GO:0004930TAS-G-protein coupled receptor activity7818539
GO:0004948IEA-calcitonin receptor activity-
GO:0005515IPI-protein binding9620797
GO:0008565IDA-protein transporter activity9620797
GO ID Evidence Qualifier GO_term References
GO:0001525IDA-angiogenesis20596610
GO:0006171IDA-cAMP biosynthetic process20074556
GO:0006816IDA-calcium ion transport10882736
GO:0007166IEA-cell surface receptor signaling pathway-
GO:0007187TAS-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger7818539
GO:0007189IEA-adenylate cyclase-activating G-protein coupled receptor signaling pathway-
GO:0007507IEA-heart development-
GO:0015031IDA-protein transport9620797
GO:0030819IDA-positive regulation of cAMP biosynthetic process10882736
GO:0030819IGI-positive regulation of cAMP biosynthetic process9620797
GO:0031623IDA-receptor internalization20074556
GO:0045986IEA-negative regulation of smooth muscle contraction-
GO:0048661IEA-positive regulation of smooth muscle cell proliferation-
GO:0050728IEA-negative regulation of inflammatory response-
GO:0071329IDA-cellular response to sucrose stimulus10882736
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RAMP1CALCRL1154989620797 11535606 12234182 12574158 14722252 Affinity Capture-Western; Co-localization; Reconstituted Complex
RAMP1CALCRL1155589620797 11535606 12234182 12574158 14722252 Affinity Capture-Western; Co-localization; Reconstituted Complex
CRCPCALCRL11812110903324 Affinity Capture-Western
CRCPCALCRL11549810903324 Affinity Capture-Western
RAMP3CALCRL11549811387328 Reconstituted Complex
RAMP3CALCRL11555911387328 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1926944
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040822-26'