AutismKB 2.0

Annotation Details for AKAP8


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Basic Information Top
Gene Symbol:AKAP8 ( AKAP95,DKFZp586B1222 )
Gene Full Name: A kinase (PRKA) anchor protein 8
Band: 19p13.12
Quick LinksEntrez ID:10270; OMIM: 604692; Uniprot ID:AKAP8_HUMAN; ENSEMBL ID: ENSG00000105127; HGNC ID: 378
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000793IEA-condensed chromosome-
GO:0001939IEA-female pronucleus-
GO:0005634TAS-nucleus9473338
GO:0005654IDA-nucleoplasm-
GO:0005730IEA-nucleolus-
GO:0005739IEA-mitochondrion-
GO:0005794IEA-Golgi apparatus-
GO:0016020IDA-membrane19946888
GO:0016363IBA-nuclear matrix-
GO:0016363ISS-nuclear matrix-
GO ID Evidence Qualifier GO_term References
GO:0003690IEA-double-stranded DNA binding-
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding9473338
GO:0008270IEA-zinc ion binding-
GO:0017151IBANOTDEAD/H-box RNA helicase binding-
GO:0034237IPI-protein kinase A regulatory subunit binding17911601
GO:0042826IDA-histone deacetylase binding16980585
GO:0051059IEA-NF-kappaB binding-
GO ID Evidence Qualifier GO_term References
GO:0000278TAS-mitotic cell cycle9473338
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0007076IEA-mitotic chromosome condensation-
GO:0007165TAS-signal transduction9473338
GO:0015031IEA-protein transport-
GO:0031065IMP-positive regulation of histone deacetylation16980585
GO:0032720IEA-negative regulation of tumor necrosis factor production-
GO:0033127IMP-regulation of histone phosphorylation16980585
GO:0044839IMP-cell cycle G2/M phase transition16980585
GO:0045087IEA-innate immune response-
GO:0071222IEA-cellular response to lipopolysaccharide-
GO:0071380IEA-cellular response to prostaglandin E stimulus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AKAP8AMY1A11556112414807 Affinity Capture-Western; Reconstituted Complex
AKAP8AMY1A10677312414807 Affinity Capture-Western; Reconstituted Complex
AKAP8CCND110706714641107 Affinity Capture-Western
AKAP8CCND111556114641107 Affinity Capture-Western
AKAP8CCND210733414641107 Affinity Capture-Western
AKAP8CCND211556114641107 Affinity Capture-Western
AKAP8CCND310733614641107 Affinity Capture-Western; Two-hybrid
AKAP8CCND311556114641107 Affinity Capture-Western; Two-hybrid
AKAP8DDX510802111279182 Far Western; Two-hybrid
AKAP8DDX511556111279182 Far Western; Two-hybrid
AKAP8MCM211556112740381 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
AKAP8MCM211033912740381 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
AKAP8PRKAR2A1115629473338 10601332 Affinity Capture-Western; Reconstituted Complex
AKAP8PRKAR2A1155619473338 10601332 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
AKAP8hCV2596739 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:1928488
  • Data Attributes: MGI curated and HomoloGene calculated
No data