AutismKB 2.0

Annotation Details for NET1


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Basic Information Top
Gene Symbol:NET1 ( ARHGEF8,NET1A )
Gene Full Name: neuroepithelial cell transforming 1
Band: 10p15.1
Quick LinksEntrez ID:10276; OMIM: 606450; Uniprot ID:ARHG8_HUMAN; ENSEMBL ID: ENSG00000173848; HGNC ID: 14592
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005829TAS-cytosol-
GO:0005886IEA-plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005085TAS-guanyl-nucleotide exchange factor activity-
GO:0005089TAS-Rho guanyl-nucleotide exchange factor activity-
GO:0005515IPI-protein binding24550280
GO:0017049IEA-GTP-Rho binding-
GO ID Evidence Qualifier GO_term References
GO:0001558NAS-regulation of cell growth8649828
GO:0007165TAS-signal transduction8649828
GO:0035023IEA-regulation of Rho protein signal transduction-
GO:0035556IEA-intracellular signal transduction-
GO:0043065IDA-positive regulation of apoptotic process21373644
GO:0043065TAS-positive regulation of apoptotic process-
GO:0043547IMP-positive regulation of GTPase activity21373644
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
GO:0051451IEA-myoblast migration-
GO:0070301IDA-cellular response to hydrogen peroxide21373644
GO:0071479IDA-cellular response to ionizing radiation21373644
GO:1900026IEA-positive regulation of substrate adhesion-dependent cell spreading-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NET1RHOA1155659535835 Two-hybrid
NET1RHOA1068809535835 Two-hybrid
NET1PRKAB211155220562859 Affinity Capture-MS
NET1PRKAB211556520562859 Affinity Capture-MS
NET1USP1111556519615732 Affinity Capture-MS
NET1USP1111386619615732 Affinity Capture-MS
NET1MAGI111465511350080 Affinity Capture-Western
NET1MAGI111556511350080 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1927138
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041121-18'