AutismKB 2.0

Annotation Details for EFS


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Basic Information Top
Gene Symbol:EFS ( CAS3,CASS3,EFS1,EFS2,HEFS,SIN )
Gene Full Name: embryonal Fyn-associated substrate
Band: 14q11.2
Quick LinksEntrez ID:10278; OMIM: 609906; Uniprot ID:EFS_HUMAN; ENSEMBL ID: ENSG00000100842; HGNC ID: 16898
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737TAS-cytoplasm9349509
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0017124IEA-SH3 domain binding-
GO:0019904IPI-protein domain specific binding11984006
GO ID Evidence Qualifier GO_term References
GO:0007155IEA-cell adhesion-
GO:0035556TAS-intracellular signal transduction9349509
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EFSLYST10755211984006 Two-hybrid
EFSLYST11556711984006 Two-hybrid
EFSPTPN121117469748319 Reconstituted Complex
EFSPTPN121155679748319 Reconstituted Complex
EFSBCAR111556716169070 Two-hybrid
EFSBCAR111493416169070 Two-hybrid
EFSSH2D3C11535516189514 Two-hybrid
EFSSH2D3C11556716189514 Two-hybrid
EFSSORBS311547516189514 Two-hybrid
EFSSORBS311556716189514 Two-hybrid
TRAPPC6AEFS12253816189514 Two-hybrid
TRAPPC6AEFS11556716189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:105311
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018