AutismKB 2.0

Annotation Details for ADAR


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Basic Information Top
Gene Symbol:ADAR ( ADAR1,DRADA,DSH,DSRAD,G1P1,IFI-4,IFI4,K88DSRBP,P136 )
Gene Full Name: adenosine deaminase, RNA-specific
Band: 1q21.3
Quick LinksEntrez ID:103; OMIM: 146920; Uniprot ID:DSRAD_HUMAN; ENSEMBL ID: ENSG00000160710; HGNC ID: 225
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus18362360
GO:0005634TAS-nucleus7565688
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005730IDA-nucleolus-
GO:0005737IDA-cytoplasm23622242
GO:0005737TAS-cytoplasm7565688
GO:0016020IDA-membrane19946888
GO:0044530IDA-supraspliceosomal complex18362360
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003723IDA-RNA binding22658674
GO:0003726IDA-double-stranded RNA adenosine deaminase activity9020165
GO:0003726NAS-double-stranded RNA adenosine deaminase activity7565688
GO:0003726TAS-double-stranded RNA adenosine deaminase activity-
GO:0005515IPI-protein binding18362360
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001649IEA-osteoblast differentiation-
GO:0001701IEA-in utero embryonic development-
GO:0002244IEA-hematopoietic progenitor cell differentiation-
GO:0002566IEA-somatic diversification of immune receptors via somatic mutation-
GO:0006382IDA-adenosine to inosine editing15858013
GO:0006382IMP-adenosine to inosine editing16475990
GO:0006382TAS-adenosine to inosine editing-
GO:0006397IEA-mRNA processing-
GO:0009615IMP-response to virus15858013
GO:0016553IDA-base conversion or substitution editing9020165
GO:0030218IEA-erythrocyte differentiation-
GO:0031054IDA-pre-miRNA processing23622242
GO:0035280IDA-miRNA loading onto RISC involved in gene silencing by miRNA23622242
GO:0035455IDA-response to interferon-alpha16475990
GO:0043066IEA-negative regulation of apoptotic process-
GO:0044387IDA-negative regulation of protein kinase activity by regulation of protein phosphorylation19651874
GO:0044387IMP-negative regulation of protein kinase activity by regulation of protein phosphorylation18362360
GO:0045070IDA-positive regulation of viral genome replication19651874
GO:0045070IMP-positive regulation of viral genome replication18362360
GO:0045071IEA-negative regulation of viral genome replication-
GO:0045087TAS-innate immune response16475990
GO:0051607IEA-defense response to virus-
GO:0060216IEA-definitive hemopoiesis-
GO:0060337TAS-type I interferon signaling pathway-
GO:0060339IEA-negative regulation of type I interferon-mediated signaling pathway-
GO:0061484IEA-hematopoietic stem cell homeostasis-
GO:0098586IEA-cellular response to virus-
GO:1900369IEA-negative regulation of RNA interference-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
XPO1ADAR11334811604520 Reconstituted Complex
XPO1ADAR10661711604520 Reconstituted Complex
HDLBPADAR10931915723802 Affinity Capture-Western
HDLBPADAR10661715723802 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1889575
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000616-5'