AutismKB 2.0

Annotation Details for CDKN2C


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Basic Information Top
Gene Symbol:CDKN2C ( INK4C,p18,p18-INK4C )
Gene Full Name: cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Band: 1p32.3
Quick LinksEntrez ID:1031; OMIM: 603369; Uniprot ID:CDN2C_HUMAN; ENSEMBL ID: ENSG00000123080; HGNC ID: 1789
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus11800646
GO:0005737IDA-cytoplasm11800646
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004861IDA-cyclin-dependent protein serine/threonine kinase inhibitor activity8001816
GO:0005515IPI-protein binding8840966
GO:0019901IPI-protein kinase binding8001816
GO ID Evidence Qualifier GO_term References
GO:0000079IDA-regulation of cyclin-dependent protein serine/threonine kinase activity8001816
GO:0000082IDA-G1/S transition of mitotic cell cycle10208428
GO:0007050IDA-cell cycle arrest10208428
GO:0008285IDA-negative regulation of cell proliferation10208428
GO:0030308IDA-negative regulation of cell growth10208428
GO:0042326IDA-negative regulation of phosphorylation10208428
GO:0045736IEA-negative regulation of cyclin-dependent protein serine/threonine kinase activity-
GO:0048709IEA-oligodendrocyte differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CDKN2CAPLP110683016169070 Two-hybrid
CDKN2CAPLP110746516169070 Two-hybrid
CDKN2CCDK41074548001816 17353931 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CDKN2CCDK41074658001816 17353931 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CDKN2CCDK61074658001816 11124804 17353931 Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid
CDKN2CCDK61074568001816 11124804 17353931 Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid
DRAP1CDKN2C10746516169070 Two-hybrid
DRAP1CDKN2C11583816169070 Two-hybrid
COPS6CDKN2C10746516169070 Two-hybrid
COPS6CDKN2C11617616169070 Two-hybrid
GDF9CDKN2C10746516169070 Two-hybrid
GDF9CDKN2C10893016169070 Two-hybrid
NHP2L1CDKN2C10746516169070 Two-hybrid
NHP2L1CDKN2C11087416169070 Two-hybrid
C1orf103CDKN2C12090516169070 Two-hybrid
C1orf103CDKN2C10746516169070 Two-hybrid
CCDC90BCDKN2C12192316169070 Two-hybrid
CCDC90BCDKN2C10746516169070 Two-hybrid
TLE1CDKN2C10746516169070 Two-hybrid
TLE1CDKN2C11294316169070 Two-hybrid
TP53CDKN2C11301016169070 Two-hybrid
TP53CDKN2C10746516169070 Two-hybrid
C7orf64CDKN2C12385516169070 Two-hybrid
C7orf64CDKN2C10746516169070 Two-hybrid
UNC119CDKN2C10746516169070 Two-hybrid
UNC119CDKN2C11454816169070 Two-hybrid
QPCTLCDKN2C12017117353931 Affinity Capture-MS
QPCTLCDKN2C10746517353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
CDKN2Crs1043141, rs11205800, rs11579642, rs12855 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:105388
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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