AutismKB 2.0

Annotation Details for TNIP1


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Basic Information Top
Gene Symbol:TNIP1 ( ABIN-1,KIAA0113,NAF1,VAN )
Gene Full Name: TNFAIP3 interacting protein 1
Band: 5q33.1
Quick LinksEntrez ID:10318; OMIM: 607714; Uniprot ID:TNIP1_HUMAN; ENSEMBL ID: ENSG00000145901; HGNC ID: 16903
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622TAS-intracellular9923610
GO:0005654IDA-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004843IDAcontributes_tothiol-dependent ubiquitin-specific protease activity16684768
GO:0005515IPI-protein binding15474016
GO:0042802IPI-identical protein binding21988832
GO:0051019IDA-mitogen-activated protein kinase binding12220502
GO ID Evidence Qualifier GO_term References
GO:0002755ISS-MyD88-dependent toll-like receptor signaling pathway-
GO:0006412TAS-translation9923610
GO:0006952TAS-defense response9923610
GO:0006954IEA-inflammatory response-
GO:0007159IMP-leukocyte cell-cell adhesion17632516
GO:0009101IDA-glycoprotein biosynthetic process9923610
GO:0016579TAS-protein deubiquitination-
GO:0043124IDA-negative regulation of I-kappaB kinase/NF-kappaB signaling16684768
GO:0045071TAS-negative regulation of viral genome replication9923610
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0050729ISS-positive regulation of inflammatory response-
GO:0070373IDA-negative regulation of ERK1 and ERK2 cascade12220502
GO:0085032IDA-modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade20010814
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TNIP1MAPK111158012220502 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TNIP1MAPK111560212220502 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TNIP1TNFAIP311298310385526 Affinity Capture-Western; Two-hybrid
TNIP1TNFAIP311560210385526 Affinity Capture-Western; Two-hybrid
TNIP1TTF211403612927788 Two-hybrid
TNIP1TTF211560212927788 Two-hybrid
MAGEB18TNIP113039816189514 Affinity Capture-Western; Two-hybrid
MAGEB18TNIP111560216189514 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1926194
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070112-1502'