AutismKB 2.0

Annotation Details for ABCA7


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Basic Information Top
Gene Symbol:ABCA7 ( ABCA-SSN,ABCX,FLJ40025 )
Gene Full Name: ATP-binding cassette, sub-family A (ABC1), member 7
Band: 19p13.3
Quick LinksEntrez ID:10347; OMIM: 605414; Uniprot ID:ABCA7_HUMAN; ENSEMBL ID: ENSG00000064687; HGNC ID: 37
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139IEA-Golgi membrane-
GO:0001891ISS-phagocytic cup-
GO:0005794IDA-Golgi apparatus-
GO:0005886IDA-plasma membrane14570867
GO:0005886TAS-plasma membrane-
GO:0009986ISS-cell surface-
GO:0016021TAS-integral component of membrane10873640
GO:0030054IDA-cell junction-
GO:0031901IEA-early endosome membrane-
GO:0032587ISS-ruffle membrane-
GO:0043190TAS-ATP-binding cassette (ABC) transporter complex10873640
GO:0043231IBA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0005215TAS-transporter activity10873640
GO:0005524IEA-ATP binding-
GO:0016887IDA-ATPase activity24097981
GO:0034188IDA-apolipoprotein A-I receptor activity14570867
GO:0042626IBA-ATPase activity, coupled to transmembrane movement of substances-
GO:0090554IDA-phosphatidylcholine-translocating ATPase activity24097981
GO:0090556IDA-phosphatidylserine-translocating ATPase activity24097981
GO ID Evidence Qualifier GO_term References
GO:0006909IEA-phagocytosis-
GO:0007613ISS-memory-
GO:0010875ISS-positive regulation of cholesterol efflux-
GO:0015917IEA-aminophospholipid transport-
GO:0018149ISS-peptide cross-linking-
GO:0033344IDA-cholesterol efflux14570867
GO:0033700IDA-phospholipid efflux14570867
GO:0034380IDA-high-density lipoprotein particle assembly14570867
GO:0034504ISS-protein localization to nucleus-
GO:0038027IDA-apolipoprotein A-I-mediated signaling pathway14570867
GO:0042985ISS-negative regulation of amyloid precursor protein biosynthetic process-
GO:0045332IDA-phospholipid translocation24097981
GO:0050766ISS-positive regulation of phagocytosis-
GO:0055085TAS-transmembrane transport-
GO:0070374ISS-positive regulation of ERK1 and ERK2 cascade-
GO:1900223ISS-positive regulation of amyloid-beta clearance-
GO:1901076ISS-positive regulation of engulfment of apoptotic cell-
GO:1902430ISS-negative regulation of amyloid-beta formation-
GO:1902995ISS-positive regulation of phospholipid efflux-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1351646
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050517-6'