AutismKB 2.0

Annotation Details for CITED2


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Basic Information Top
Gene Symbol:CITED2 ( MRG1,P35SRJ )
Gene Full Name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Band: 6q24.1
Quick LinksEntrez ID:10370; OMIM: 602937; Uniprot ID:CITE2_HUMAN; ENSEMBL ID: ENSG00000164442; HGNC ID: 1987
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790ISS-nuclear chromatin-
GO:0005634IDA-nucleus9434189
GO:0005654TAS-nucleoplasm-
GO:0043234IMP-protein complex14594809
GO ID Evidence Qualifier GO_term References
GO:0001105IBA-RNA polymerase II transcription coactivator activity-
GO:0001106IDA-RNA polymerase II transcription corepressor activity22735262
GO:0003682ISS-chromatin binding-
GO:0003700ISS-transcription factor activity, sequence-specific DNA binding-
GO:0003713IDA-transcription coactivator activity11581164
GO:0003714IDA-transcription corepressor activity9887100
GO:0003714IMP-transcription corepressor activity17906695
GO:0005515IPI-protein binding9887100
GO:0019904IPI-protein domain specific binding14594809
GO:0035035IDA-histone acetyltransferase binding22735262
GO:0050693IPI-LBD domain binding15051727
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter17906695
GO:0001666IDA-response to hypoxia9887100
GO:0001666IMP-response to hypoxia17906695
GO:0001889ISS-liver development-
GO:0003151ISS-outflow tract morphogenesis-
GO:0003156ISS-regulation of animal organ formation-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007368ISS-determination of left/right symmetry-
GO:0007507IMP-heart development16287139
GO:0007507ISS-heart development-
GO:0007530IBA-sex determination-
GO:0007530ISS-sex determination-
GO:0008283IDA-cell proliferation15051727
GO:0010628IDA-positive regulation of gene expression15051727
GO:0010629IDA-negative regulation of gene expression15051727
GO:0022409ISS-positive regulation of cell-cell adhesion-
GO:0030154IEA-cell differentiation-
GO:0030336IMP-negative regulation of cell migration18054336
GO:0030511ISS-positive regulation of transforming growth factor beta receptor signaling pathway-
GO:0034405IMP-response to fluid shear stress12960175
GO:0035360IDA-positive regulation of peroxisome proliferator activated receptor signaling pathway15051727
GO:0035802ISS-adrenal cortex formation-
GO:0043066ISS-negative regulation of apoptotic process-
GO:0043627IDA-response to estrogen11581164
GO:0045787ISS-positive regulation of cell cycle-
GO:0045892IDA-negative regulation of transcription, DNA-templated15051727
GO:0045892IMP-negative regulation of transcription, DNA-templated9887100
GO:0045893IDA-positive regulation of transcription, DNA-templated9434189
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter22735262
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0045944TAS-positive regulation of transcription from RNA polymerase II promoter-
GO:0048536ISS-spleen development-
GO:0060412ISS-ventricular septum morphogenesis-
GO:0060971ISS-embryonic heart tube left/right pattern formation-
GO:0060972IBA-left/right pattern formation-
GO:0061428IDA-negative regulation of transcription from RNA polymerase II promoter in response to hypoxia22735262
GO:0070986ISS-left/right axis specification-
GO:1900164ISS-nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry-
GO:2000020ISS-positive regulation of male gonad development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CITED2CREBBP1156499887100 Affinity Capture-Western
CITED2CREBBP1077779887100 Affinity Capture-Western
CITED2EP3001083479887100 10593900 11744733 12586840 15154850 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CITED2EP3001156499887100 10593900 11744733 12586840 15154850 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CITED2SMAD211564916619037 Affinity Capture-Western
CITED2SMAD211026216619037 Affinity Capture-Western
CITED2SMAD311564916619037 Affinity Capture-Western; Reconstituted Complex
CITED2SMAD311026316619037 Affinity Capture-Western; Reconstituted Complex
CITED2TBP11564910593900 Reconstituted Complex
CITED2TBP11277110593900 Reconstituted Complex
CITED2TFAP2A11564911744733 12586840 Far Western; Reconstituted Complex; Two-hybrid
CITED2TFAP2A11287811744733 12586840 Far Western; Reconstituted Complex; Two-hybrid
CITED2TFAP2B11564911744733 Reconstituted Complex
CITED2TFAP2B11287911744733 Reconstituted Complex
CITED2TFAP2C11564911744733 12586840 Reconstituted Complex; Two-hybrid
CITED2TFAP2C11288011744733 12586840 Reconstituted Complex; Two-hybrid
CITED2LHX311564910593900 Two-hybrid
CITED2LHX311371810593900 Two-hybrid
CITED2LHX211564910593900 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CITED2LHX211475810593900 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1306784
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041010-141'