AutismKB 2.0

Annotation Details for NOD1


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Basic Information Top
Gene Symbol:NOD1 ( CARD4,CLR7.1,NLRC1 )
Gene Full Name: nucleotide-binding oligomerization domain containing 1
Band: 7p14.3
Quick LinksEntrez ID:10392; OMIM: 605980; Uniprot ID:NOD1_HUMAN; ENSEMBL ID: ENSG00000106100; HGNC ID: 16390
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm10329646
GO:0005737TAS-cytoplasm15967716
GO:0005829TAS-cytosol-
GO:0016323IDA-basolateral plasma membrane19043560
GO:0016324IEA-apical plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15107016
GO:0005524IEA-ATP binding-
GO:0008656TAS-cysteine-type endopeptidase activator activity involved in apoptotic process10329646
GO:0042802IDA-identical protein binding10329646
GO:0042802IPI-identical protein binding18186648
GO:0042803IPI-protein homodimerization activity18186648
GO:0042834TAS-peptidoglycan binding15967716
GO:0050700IDA-CARD domain binding10329646
GO ID Evidence Qualifier GO_term References
GO:0000187TAS-activation of MAPK activity-
GO:0002606ISS-positive regulation of dendritic cell antigen processing and presentation-
GO:0006915IEA-apoptotic process-
GO:0006919IDA-activation of cysteine-type endopeptidase activity involved in apoptotic process10329646
GO:0006952TAS-defense response15967716
GO:0006954TAS-inflammatory response15967716
GO:0007165TAS-signal transduction15967716
GO:0007254TAS-JNK cascade-
GO:0009595TAS-detection of biotic stimulus15967716
GO:0016045IDA-detection of bacterium15653568
GO:0016579TAS-protein deubiquitination-
GO:0032731IEA-positive regulation of interleukin-1 beta production-
GO:0032755IEA-positive regulation of interleukin-6 production-
GO:0032760IEA-positive regulation of tumor necrosis factor production-
GO:0035556IDA-intracellular signal transduction15653568
GO:0042228IDA-interleukin-8 biosynthetic process15653568
GO:0042742IDA-defense response to bacterium15653568
GO:0043123IDA-positive regulation of I-kappaB kinase/NF-kappaB signaling10329646
GO:0043280IDA-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process10329646
GO:0045087IEA-innate immune response-
GO:0046330IEA-positive regulation of JNK cascade-
GO:0050830IEA-defense response to Gram-positive bacterium-
GO:0051000IEA-positive regulation of nitric-oxide synthase activity-
GO:0051092IDA-positive regulation of NF-kappaB transcription factor activity17054981
GO:0051092TAS-positive regulation of NF-kappaB transcription factor activity-
GO:0051259TAS-protein oligomerization15967716
GO:0070374IEA-positive regulation of ERK1 and ERK2 cascade-
GO:0070423TAS-nucleotide-binding oligomerization domain containing signaling pathway-
GO:0071225IMP-cellular response to muramyl dipeptide25093298
GO:1901224IMP-positive regulation of NIK/NF-kappaB signaling25093298
GO:1904417IEA-positive regulation of xenophagy-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NOD1CASP110728410329646 Affinity Capture-Western
NOD1CASP111566410329646 Affinity Capture-Western
NOD1CASP211566410329646 Affinity Capture-Western
NOD1CASP210728510329646 Affinity Capture-Western
NOD1CASP411566410329646 Affinity Capture-Western
NOD1CASP410728710329646 Affinity Capture-Western
NOD1CASP811566410329646 Affinity Capture-Western
NOD1CASP810729110329646 Affinity Capture-Western
NOD1CASP911566410329646 Affinity Capture-Western
NOD1CASP910729210329646 Affinity Capture-Western
NOD1RIPK211566410329646 Affinity Capture-Western
NOD1RIPK211430010329646 Affinity Capture-Western
NOD1CFLAR11436410329646 Affinity Capture-Western
NOD1CFLAR11566410329646 Affinity Capture-Western
NOD1NOD111566410329646 Affinity Capture-Western
CARD6NOD112419312775719 Affinity Capture-Western
CARD6NOD111566412775719 Affinity Capture-Western
NLRC4NOD111566415107016 Affinity Capture-Western
NLRC4NOD112181415107016 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1341839
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-071116-9'