AutismKB 2.0

Annotation Details for CDX2


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Basic Information Top
Gene Symbol:CDX2 ( CDX-3,CDX3 )
Gene Full Name: caudal type homeobox 2
Band: 13q12.2
Quick LinksEntrez ID:1045; OMIM: 600297; Uniprot ID:CDX2_HUMAN; ENSEMBL ID: ENSG00000165556; HGNC ID: 1806
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000794IEA-condensed nuclear chromosome-
GO:0005634IBA-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0017053IEA-transcriptional repressor complex-
GO:0043234IEA-protein complex-
GO ID Evidence Qualifier GO_term References
GO:0000980IDA-RNA polymerase II distal enhancer sequence-specific DNA binding15677472
GO:0001227IDA-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding15677472
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding9459001
GO:0003714IEA-transcription corepressor activity-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter15677472
GO:0001568IEA-blood vessel development-
GO:0001829IEA-trophectodermal cell differentiation-
GO:0006366TAS-transcription from RNA polymerase II promoter9459001
GO:0008284IEA-positive regulation of cell proliferation-
GO:0008333IEA-endosome to lysosome transport-
GO:0009887TAS-animal organ morphogenesis9052785
GO:0009948IBA-anterior/posterior axis specification-
GO:0014807ISS-regulation of somitogenesis-
GO:0030154IBA-cell differentiation-
GO:0035019IEA-somatic stem cell population maintenance-
GO:0045197IEA-establishment or maintenance of epithelial cell apical/basal polarity-
GO:0045597IEA-positive regulation of cell differentiation-
GO:0045893IEA-positive regulation of transcription, DNA-templated-
GO:0060575ISS-intestinal epithelial cell differentiation-
GO:0060711IEA-labyrinthine layer development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EP300CDX210834710506141 Affinity Capture-Western; Reconstituted Complex
EP300CDX210747510506141 Affinity Capture-Western; Reconstituted Complex
PAX6CDX211111410506141 Affinity Capture-Western; Reconstituted Complex
PAX6CDX210747510506141 Affinity Capture-Western; Reconstituted Complex
HNF1ACDX211278910677375 Reconstituted Complex
HNF1ACDX210747510677375 Reconstituted Complex
KDM5BCDX211598419336002 Affinity Capture-MS
KDM5BCDX210747519336002 Affinity Capture-MS
SMARCA2CDX211247919371634 Affinity Capture-Western; Reconstituted Complex
SMARCA2CDX210747519371634 Affinity Capture-Western; Reconstituted Complex
SMARCA4CDX211248119371634 Reconstituted Complex
SMARCA4CDX210747519371634 Reconstituted Complex
SMARCB1CDX211248219371634 Reconstituted Complex
SMARCB1CDX210747519371634 Reconstituted Complex
SMARCD1CDX211248619371634 Reconstituted Complex
SMARCD1CDX210747519371634 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
CDX2rs1805107 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:88361
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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