AutismKB 2.0

Annotation Details for CREB3


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Basic Information Top
Gene Symbol:CREB3 ( LUMAN,LZIP,MGC15333,MGC19782 )
Gene Full Name: cAMP responsive element binding protein 3
Band: 9p13.3
Quick LinksEntrez ID:10488; OMIM: 606443; Uniprot ID:CREB3_HUMAN; ENSEMBL ID: ENSG00000107175; HGNC ID: 2347
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139TAS-Golgi membrane-
GO:0005634IC-nucleus16940180
GO:0005634IDA-nucleus20546900
GO:0005654TAS-nucleoplasm-
GO:0005783IDA-endoplasmic reticulum16236796
GO:0005789IEA-endoplasmic reticulum membrane-
GO:0005829IDA-cytosol-
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding16940180
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding16940180
GO:0000982IDA-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding16940180
GO:0001077IMP-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding16940180
GO:0005515IPI-protein binding10629049
GO:0035497IEA-cAMP response element binding-
GO ID Evidence Qualifier GO_term References
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0006935IEA-chemotaxis-
GO:0006990IDA-positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response16940180
GO:0016032IEA-viral process-
GO:0030968TAS-endoplasmic reticulum unfolded protein response-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter16940180
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter16940180
GO:0090026IDA-positive regulation of monocyte chemotaxis17296613
GO:1902236IDA-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway16940180
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CREB3BNIP211575116189514 Two-hybrid
CREB3BNIP210713116189514 Two-hybrid
CREB3EMD11575116189514 Two-hybrid
CREB3EMD10832516189514 Two-hybrid
CREB3HCFC11157519389645 9658067 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CREB3HCFC11093049389645 9658067 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CREB3MALL11575116189514 Two-hybrid
CREB3MALL11360616189514 Two-hybrid
CREB3STX811486716189514 Two-hybrid
CREB3STX811575116189514 Two-hybrid
APPBP2CREB311575116189514 Two-hybrid
APPBP2CREB311576916189514 Two-hybrid
No data
Gene Symbol Interactant Interaction ID References Description
CREB3NFIL30733912805554 -
CREB3NFIL30561912805554 -
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99946
  • Data Attributes: MGI curated and HomoloGene calculated