Gene Symbol:	UNC13B ( MGC133279,MGC133280,MUNC13,UNC13,Unc13h2,hmunc13 )
Gene Full Name:	unc-13 homolog B (C. elegans)
Band:	9p13.3
Quick Links	Entrez ID:10497; OMIM: 605836; Uniprot ID:UN13B_HUMAN; ENSEMBL ID: ENSG00000198722; HGNC ID: 12566
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005794	IDA	-	Golgi apparatus	10233166
GO:0005829	IDA	-	cytosol	10233166
GO:0005829	TAS	-	cytosol	-
GO:0005886	ISS	-	plasma membrane	-
GO:0016020	IDA	-	membrane	9607201
GO:0030054	IEA	-	cell junction	-
GO:0031594	IEA	-	neuromuscular junction	-
GO:0032009	IEA	-	early phagosome	-
GO:0043195	IBA	-	terminal bouton	-
GO:0043195	ISS	-	terminal bouton	-
GO:0044305	IEA	-	calyx of Held	-
GO:0048786	TAS	-	presynaptic active zone	15217342
GO:0097470	IEA	-	ribbon synapse	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0005515	IPI	-	protein binding	16138900
GO:0005516	ISS	-	calmodulin binding	-
GO:0017137	NAS	-	Rab GTPase binding	19641095
GO:0019992	NAS	-	diacylglycerol binding	10233166
GO:0030742	IPI	-	GTP-dependent protein binding	16138900
GO:0046872	IEA	-	metal ion binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0007268	ISS	-	chemical synaptic transmission	-
GO:0007269	TAS	-	neurotransmitter secretion	-
GO:0007528	IEA	-	neuromuscular junction development	-
GO:0010808	ISS	-	positive regulation of synaptic vesicle priming	-
GO:0014047	TAS	-	glutamate secretion	-
GO:0016079	IBA	-	synaptic vesicle exocytosis	-
GO:0016081	IEA	-	synaptic vesicle docking	-
GO:0016082	ISS	-	synaptic vesicle priming	-
GO:0031914	IEA	-	negative regulation of synaptic plasticity	-
GO:0035249	IEA	-	synaptic transmission, glutamatergic	-
GO:0035556	IEA	-	intracellular signal transduction	-
GO:0043065	IDA	-	positive regulation of apoptotic process	10233166
GO:0048172	IEA	-	regulation of short-term neuronal synaptic plasticity	-
GO:0050714	IDA	-	positive regulation of protein secretion	19641095
GO:0060384	IEA	-	innervation	-
GO:0071333	IDA	-	cellular response to glucose stimulus	19641095
GO:0090382	IEA	-	phagosome maturation	-
GO:0097151	ISS	-	positive regulation of inhibitory postsynaptic potential	-
GO:0099525	IEA	-	presynaptic dense core vesicle exocytosis	-
GO:1900426	IEA	-	positive regulation of defense response to bacterium	-

Gene Symbol	Interactant	Interaction ID	References	Description
UNC13B	SNAP25	115759	8999968	Co-fractionation
UNC13B	SNAP25	112500	8999968	Co-fractionation
UNC13B	SPTBN2	115759	9704016	Reconstituted Complex; Two-hybrid
UNC13B	SPTBN2	112590	9704016	Reconstituted Complex; Two-hybrid
UNC13B	STX1A	115759	8999968	Co-fractionation; Two-hybrid
UNC13B	STX1A	112676	8999968	Co-fractionation; Two-hybrid
UNC13B	VAMP2	115759	8999968	Co-fractionation
UNC13B	VAMP2	112711	8999968	Co-fractionation
UNC13B	DOC2A	114026	9195900 9736751	Co-fractionation; Reconstituted Complex; Two-hybrid
UNC13B	DOC2A	115759	9195900 9736751	Co-fractionation; Reconstituted Complex; Two-hybrid
UNC13B	RPH3AL	115759	14593078	Reconstituted Complex
UNC13B	RPH3AL	114880	14593078	Reconstituted Complex
STX1B	UNC13B	115759	8999968	Co-fractionation; Two-hybrid
STX1B	UNC13B	125203	8999968	Co-fractionation; Two-hybrid
RIMS1	UNC13B	115759	11343654 12163476	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RIMS1	UNC13B	116646	11343654 12163476	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
WDR48	UNC13B	115759	19615732	Affinity Capture-MS
WDR48	UNC13B	121649	19615732	Affinity Capture-MS

AutismKB 2.0

Annotation Details for UNC13B