AutismKB 2.0

Annotation Details for DDX17


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Basic Information Top
Gene Symbol:DDX17 ( DKFZp761H2016,P72,RH70 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
Band: 22q13.1
Quick LinksEntrez ID:10521; OMIM: 608469; Uniprot ID:DDX17_HUMAN; ENSEMBL ID: ENSG00000100201; HGNC ID: 2740
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus24910439
GO:0005654TAS-nucleoplasm-
GO:0005730IEA-nucleolus-
GO:0005829IEA-cytosol-
GO:0016020IDA-membrane19946888
GO:0016607IDA-nuclear speck-
GO ID Evidence Qualifier GO_term References
GO:0003713IDA-transcription coactivator activity17226766
GO:0003723IDA-RNA binding22658674
GO:0003724TAS-RNA helicase activity8871553
GO:0004004IBA-ATP-dependent RNA helicase activity-
GO:0005515IPI-protein binding14559993
GO:0005524IEA-ATP binding-
GO:0008186TAS-RNA-dependent ATPase activity8871553
GO:0030331IDA-estrogen receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0000380IMP-alternative mRNA splicing, via spliceosome24275493
GO:0000381IMP-regulation of alternative mRNA splicing, via spliceosome23022728
GO:0001837IMP-epithelial to mesenchymal transition24910439
GO:0006351IEA-transcription, DNA-templated-
GO:0006357IMP-regulation of transcription from RNA polymerase II promoter24275493
GO:0006364IEA-rRNA processing-
GO:0006396TAS-RNA processing8871553
GO:0010501IBA-RNA secondary structure unwinding-
GO:0010586IMP-miRNA metabolic process27478153
GO:0030520IMP-intracellular estrogen receptor signaling pathway24275493
GO:0030521IMP-androgen receptor signaling pathway24275493
GO:0031047IEA-gene silencing by RNA-
GO:0033148IDA-positive regulation of intracellular estrogen receptor signaling pathway-
GO:0045445ISS-myoblast differentiation-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter17226766
GO:0051607IEA-defense response to virus-
GO:2001014IMP-regulation of skeletal muscle cell differentiation17011493
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DDX17APBB111577616055720 Affinity Capture-MS
DDX17APBB110681916055720 Affinity Capture-MS
DDX17AIRE10682320085707 Affinity Capture-MS
DDX17AIRE11577620085707 Affinity Capture-MS
DDX17CREBBP11577617226766 Affinity Capture-Western; Reconstituted Complex
DDX17CREBBP10777717226766 Affinity Capture-Western; Reconstituted Complex
DDX17DDX511577611250900 Phenotypic Suppression
DDX17DDX510802111250900 Phenotypic Suppression
DDX17EP30010834717226766 Affinity Capture-Western; Reconstituted Complex
DDX17EP30011577617226766 Affinity Capture-Western; Reconstituted Complex
DDX17ESR110840311250900 Affinity Capture-Western; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex
DDX17ESR111577611250900 Affinity Capture-Western; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex
DDX17ESR211577611250900 Reconstituted Complex
DDX17ESR210840411250900 Reconstituted Complex
DDX17FOS11577617226766 Affinity Capture-Luminescence
DDX17FOS10863617226766 Affinity Capture-Luminescence
DDX17HDAC111577615298701 Affinity Capture-Western
DDX17HDAC110931515298701 Affinity Capture-Western
DDX17HNRNPA111577617643375 Affinity Capture-MS
DDX17HNRNPA110942017643375 Affinity Capture-MS
DDX17HNRNPH111577617643375 Affinity Capture-MS
DDX17HNRNPH110942817643375 Affinity Capture-MS
DDX17MDM211577617226766 Affinity Capture-Luminescence
DDX17MDM211035817226766 Affinity Capture-Luminescence
DDX17PIN111577616055720 Affinity Capture-MS
DDX17PIN111131716055720 Affinity Capture-MS
DDX17SUMO211249719394292 Affinity Capture-MS
DDX17SUMO211577619394292 Affinity Capture-MS
DDX17SNRNP7011577612193588 Co-purification
DDX17SNRNP7011250912193588 Co-purification
DDX17SF111336816189514 Two-hybrid
DDX17SF111577616189514 Two-hybrid
DDX17NCOA311577611250900 Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
DDX17NCOA311384111250900 Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
DDX17NCOA111420011250900 Co-fractionation; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
DDX17NCOA111577611250900 Co-fractionation; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
DDX17KAT2B11577617226766 Affinity Capture-Western
DDX17KAT2B11437517226766 Affinity Capture-Western
DDX17SRA111577611250900 Phenotypic Enhancement; Phenotypic Suppression; Protein-RNA
DDX17SRA111532911250900 Phenotypic Enhancement; Phenotypic Suppression; Protein-RNA
DDX17SORBS311577616189514 Two-hybrid
DDX17SORBS311547516189514 Two-hybrid
DDX17NCOA211577611250900 Affinity Capture-Western; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
DDX17NCOA211576111250900 Affinity Capture-Western; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
WBP11DDX1711577616189514 Two-hybrid
WBP11DDX1711970216189514 Two-hybrid
LNX1DDX1711577616189514 Two-hybrid
LNX1DDX1712421916189514 Two-hybrid
KHDRBS2DDX1711577617643375 Affinity Capture-MS
KHDRBS2DDX1712843617643375 Affinity Capture-MS
MEPCEDDX1711577617643375 Affinity Capture-MS
MEPCEDDX1712112217643375 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1914290
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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