AutismKB 2.0

Annotation Details for TXNRD2


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Basic Information Top
Gene Symbol:TXNRD2 ( SELZ,TR,TR-BETA,TR3,TRXR2 )
Gene Full Name: thioredoxin reductase 2
Band: 22q11.21
Quick LinksEntrez ID:10587; OMIM: 606448; Uniprot ID:TRXR2_HUMAN; ENSEMBL ID: ENSG00000184470; HGNC ID: 18155
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IDA-mitochondrion10215850
GO:0005759TAS-mitochondrial matrix-
GO:0005829IDA-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004791EXP-thioredoxin-disulfide reductase activity17707404
GO:0004791IBA-thioredoxin-disulfide reductase activity-
GO:0004791ISS-thioredoxin-disulfide reductase activity-
GO:0005515IPI-protein binding20413580
GO:0050660IEA-flavin adenine dinucleotide binding-
GO ID Evidence Qualifier GO_term References
GO:0000305TAS-response to oxygen radical10455115
GO:0034599TAS-cellular response to oxidative stress-
GO:0045454IBA-cell redox homeostasis-
GO:0055114IEA-oxidation-reduction process-
GO:0098869IEA-cellular oxidant detoxification-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TXNRD2GTF2H110922015625236 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TXNRD2GTF2H111583615625236 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TXNRD2PSMC311167511463857 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TXNRD2PSMC311583611463857 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TXNRD2NCOR111497311463857 18978041 Affinity Capture-Western; Reconstituted Complex
TXNRD2NCOR111583611463857 18978041 Affinity Capture-Western; Reconstituted Complex
TXNRD2NCOA211576112612084 Two-hybrid
TXNRD2NCOA211583612612084 Two-hybrid
NCOA6TXNRD211669111158331 Reconstituted Complex; Two-hybrid
NCOA6TXNRD211583611158331 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
TXNRD2TXNRD2_V10, TXNRD2_V9, rs5748489, rs5993875, rs7287604, rs7290448, rs9617850 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1347023
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081104-217'