AutismKB 2.0

Annotation Details for PRPF8


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Basic Information Top
Gene Symbol:PRPF8 ( HPRP8,PRP8,PRPC8,RP13 )
Gene Full Name: PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
Band: 17p13.3
Quick LinksEntrez ID:10594; OMIM: 607300; Uniprot ID:PRP8_HUMAN; ENSEMBL ID: ENSG00000174231; HGNC ID: 17340
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus22720776
GO:0005654TAS-nucleoplasm-
GO:0005682TAS-U5 snRNP9774689
GO:0016020IDA-membrane19946888
GO:0016607IEA-nuclear speck-
GO:0046540IDA-U4/U6 x U5 tri-snRNP complex23793891
GO:0071013IDA-catalytic step 2 spliceosome11991638
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding9774689
GO:0017070IEA-U6 snRNA binding-
GO:0030623IEA-U5 snRNA binding-
GO:0070530IDA-K63-linked polyubiquitin binding20595234
GO ID Evidence Qualifier GO_term References
GO:0000244IDA-spliceosomal tri-snRNP complex assembly20595234
GO:0000375TAS-RNA splicing, via transesterification reactions9774689
GO:0000398IC-mRNA splicing, via spliceosome11991638
GO:0000398TAS-mRNA splicing, via spliceosome-
GO:0006397TAS-mRNA processing9774689
GO:0008380TAS-RNA splicing9774689
GO:0071222IEA-cellular response to lipopolysaccharide-
GO:0071356IEA-cellular response to tumor necrosis factor-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PRPF8ABCA111584212054535 Two-hybrid
PRPF8ABCA110653712054535 Two-hybrid
PRPF8MYC11584217353931 Affinity Capture-MS
PRPF8MYC11069417353931 Affinity Capture-MS
PRPF8NEDD411584216055720 Affinity Capture-MS
PRPF8NEDD411081116055720 Affinity Capture-MS
PRPF8PIN111584216055720 Affinity Capture-MS
PRPF8PIN111131716055720 Affinity Capture-MS
PRPF8SNRPB11251217353931 Affinity Capture-MS
PRPF8SNRPB11584217353931 Affinity Capture-MS
PRPF8UBC11316418425143 Affinity Capture-Western
PRPF8UBC11584218425143 Affinity Capture-Western
PRPF8PRPF411584219615732 Affinity Capture-MS
PRPF8PRPF411457619615732 Affinity Capture-MS
PRPF8EFTUD21158429774689 Far Western; Reconstituted Complex
PRPF8EFTUD21147499774689 Far Western; Reconstituted Complex
PRPF8SNRNP401158429774689 17353931 Affinity Capture-MS; Far Western; Reconstituted Complex
PRPF8SNRNP401148059774689 17353931 Affinity Capture-MS; Far Western; Reconstituted Complex
PRPF8SRRM111554416159877 Affinity Capture-MS
PRPF8SRRM111584216159877 Affinity Capture-MS
PRPF8CD2BP211584217353931 Affinity Capture-MS
PRPF8CD2BP211569017353931 Affinity Capture-MS
RNU12-2PPRPF811584215146077 Affinity Capture-MS
RNU12-2PPRPF811787215146077 Affinity Capture-MS
RNU11PRPF811584215146077 Affinity Capture-MS
RNU11PRPF811787315146077 Affinity Capture-MS
RNPS1PRPF811612517353931 Affinity Capture-MS
RNPS1PRPF811584217353931 Affinity Capture-MS
MEPCEPRPF811584217643375 Affinity Capture-MS
MEPCEPRPF812112217643375 Affinity Capture-MS
USP39PRPF811593919615732 Affinity Capture-MS
USP39PRPF811584219615732 Affinity Capture-MS
GIGYF2PRPF811584220696395 Affinity Capture-MS
GIGYF2PRPF811752020696395 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2179381
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-577'