Annotation Details for ERN2


Gene Symbol: | ERN2 ( IRE1b ) |
---|---|
Gene Full Name: | endoplasmic reticulum to nucleus signaling 2 |
Band: | 16p12.2 |
Quick Links | Entrez ID:10595; OMIM: 604034; Uniprot ID:ERN2_HUMAN; ENSEMBL ID: ENSG00000134398; HGNC ID: 16942 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0016021 | IEA | - | integral component of membrane | - |
GO:1990604 | ISS | - | IRE1-TRAF2-ASK1 complex | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000287 | IDA | - | magnesium ion binding | 11175748 |
GO:0004519 | IDA | - | endonuclease activity | 11175748 |
GO:0004540 | IEA | - | ribonuclease activity | - |
GO:0004674 | IDA | - | protein serine/threonine kinase activity | 11175748 |
GO:0005524 | IDA | - | ATP binding | 11175748 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0006351 | IEA | - | transcription, DNA-templated | - |
GO:0006397 | IEA | - | mRNA processing | - |
GO:0006468 | IDA | - | protein phosphorylation | 11175748 |
GO:0007050 | IEA | - | cell cycle arrest | - |
GO:0007257 | IEA | - | activation of JUN kinase activity | - |
GO:0016075 | IDA | - | rRNA catabolic process | 11175748 |
GO:0030263 | IMP | - | apoptotic chromosome condensation | 11175748 |
GO:0034976 | TAS | - | response to endoplasmic reticulum stress | 22013210 |
GO:0045892 | IMP | - | negative regulation of transcription, DNA-templated | 11175748 |
GO:0070059 | IEA | - | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | - |
GO:0090501 | IEA | - | RNA phosphodiester bond hydrolysis | - |
- MGI ID: MGI:1349436
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-090312-15