AutismKB 2.0

Annotation Details for CENPE


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Basic Information Top
Gene Symbol:CENPE ( KIF10 )
Gene Full Name: centromere protein E, 312kDa
Band: 4q24
Quick LinksEntrez ID:1062; OMIM: 117143; Uniprot ID:CENPE_HUMAN; ENSEMBL ID: ENSG00000138778; HGNC ID: 1856
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000775IDA-chromosome, centromeric region2022189
GO:0000776IDA-kinetochore11682612
GO:0000779IDA-condensed chromosome, centromeric region19465021
GO:0000940TAScolocalizes_withcondensed chromosome outer kinetochore9763420
GO:0005634IMP-nucleus9763420
GO:0005694IDA-chromosome2022189
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005871IBA-kinesin complex-
GO:0005874IDA-microtubule7889940
GO:0015630IDA-microtubule cytoskeleton-
GO:0016020IDA-membrane19946888
GO:0030496IDA-midbody2022189
GO:1990023IDA-mitotic spindle midzone2022189
GO ID Evidence Qualifier GO_term References
GO:0003777IMP-microtubule motor activity7889940
GO:0005515IPI-protein binding9763420
GO:0005524IEA-ATP binding-
GO:0008017IEA-microtubule binding-
GO:0016887IBA-ATPase activity-
GO:0043515IDA-kinetochore binding9763420
GO ID Evidence Qualifier GO_term References
GO:0000278IMP-mitotic cell cycle24748105
GO:0006890TAS-retrograde vesicle-mediated transport, Golgi to ER-
GO:0007018TAS-microtubule-based movement-
GO:0007059IMP-chromosome segregation24748105
GO:0007062TAS-sister chromatid cohesion-
GO:0007079TAS-mitotic chromosome movement towards spindle pole1406971
GO:0007080IMP-mitotic metaphase plate congression15843429
GO:0007275IEA-multicellular organism development-
GO:0019886TAS-antigen processing and presentation of exogenous peptide antigen via MHC class II-
GO:0030071IMP-regulation of mitotic metaphase/anaphase transition2022189
GO:0045860IMP-positive regulation of protein kinase activity12925705
GO:0051301IEA-cell division-
GO:0051310IMP-metaphase plate congression23891108
GO:0051315IMP-attachment of mitotic spindle microtubules to kinetochore15843429
GO:0051382NAS-kinetochore assembly9763420
GO:0099607IMP-lateral attachment of mitotic spindle microtubules to kinetochore23891108
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CENPEBUB1B1074919763420 Affinity Capture-Western
CENPEBUB1B1071669763420 Affinity Capture-Western
MAPK1CENPE1074919744883 Affinity Capture-Western; Biochemical Activity
MAPK1CENPE1115809744883 Affinity Capture-Western; Biochemical Activity
PRC1CENPE11451715297875 Affinity Capture-Western; Reconstituted Complex
PRC1CENPE10749115297875 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1098230
  • Data Attributes: MGI curated and HomoloGene calculated
No data