AutismKB 2.0

Annotation Details for TXNIP


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Basic Information Top
Gene Symbol:TXNIP ( EST01027,HHCPA78,THIF,VDUP1 )
Gene Full Name: thioredoxin interacting protein
Band: 1q21.1
Quick LinksEntrez ID:10628; OMIM: 606599; Uniprot ID:TXNIP_HUMAN; ENSEMBL ID: ENSG00000117289; HGNC ID: 16952
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005737IDA-cytoplasm14632196
GO:0005758IEA-mitochondrial intermembrane space-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004857IEA-enzyme inhibitor activity-
GO:0005515IPI-protein binding10814541
GO:0031625IPI-ubiquitin protein ligase binding20068034
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0006351IEA-transcription, DNA-templated-
GO:0006606IEA-protein import into nucleus-
GO:0007049IEA-cell cycle-
GO:0009612IEA-response to mechanical stimulus-
GO:0009749IEA-response to glucose-
GO:0030216IDA-keratinocyte differentiation14632196
GO:0032355IEA-response to estradiol-
GO:0032570IEA-response to progesterone-
GO:0042127IEA-regulation of cell proliferation-
GO:0042493IEA-response to drug-
GO:0042542IEA-response to hydrogen peroxide-
GO:0043065IEA-positive regulation of apoptotic process-
GO:0043086IEA-negative regulation of catalytic activity-
GO:0048008IEA-platelet-derived growth factor receptor signaling pathway-
GO:0051592IEA-response to calcium ion-
GO:0051782IDA-negative regulation of cell division18541147
GO:0071228IDA-cellular response to tumor cell18541147
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TXNIPHDAC111587212821938 Affinity Capture-Western
TXNIPHDAC110931512821938 Affinity Capture-Western
TXNIPTXN11587210419473 Reconstituted Complex; Two-hybrid
TXNIPTXN11314610419473 Reconstituted Complex; Two-hybrid
TXNIPZBTB1611587212821938 Affinity Capture-Western
TXNIPZBTB1611349812821938 Affinity Capture-Western
TXNIPSCEL11432414632196 Two-hybrid
TXNIPSCEL11587214632196 Two-hybrid
ZBTB32TXNIP11796412821938 Affinity Capture-Western; Two-hybrid
ZBTB32TXNIP11587212821938 Affinity Capture-Western; Two-hybrid
Gene Symbol Interactant Interaction ID References Description
TXNIPTXN21750315234975 TXNIP (TBP-2) interacts with TXN (TRX).
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1889549
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030804-10'