Annotation Details for CES1

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Basic Information Top

Gene Symbol:	CES1 ( ACAT,CEH,CES2,HMSE,HMSE1,MGC117365,PCE-1,SES1,TGH )
Gene Full Name:	carboxylesterase 1
Band:	16q12.2
Quick Links	Entrez ID:1066; OMIM: 114835; Uniprot ID:EST1_HUMAN; ENSEMBL ID: ENSG00000198848; HGNC ID: 1863
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:3 results
Biological Process:7 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005783	IDA	-	endoplasmic reticulum	-
GO:0005788	TAS	-	endoplasmic reticulum lumen	-
GO:0005829	IEA	-	cytosol	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004771	IDA	-	sterol esterase activity	11015575
GO:0047374	IEA	-	methylumbelliferyl-acetate deacetylase activity	-
GO:0052689	TAS	-	carboxylic ester hydrolase activity	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0006695	IDA	-	cholesterol biosynthetic process	11015575
GO:0006805	TAS	-	xenobiotic metabolic process	-
GO:0008152	TAS	-	metabolic process	1918003
GO:0009636	TAS	-	response to toxic substance	1918003
GO:0030855	IDA	-	epithelial cell differentiation	21492153
GO:0051791	IDA	-	medium-chain fatty acid metabolic process	11015575
GO:0090122	TAS	-	cholesterol ester hydrolysis involved in cholesterol transport	11015575

Protein-Protein Interaction

BioGRID:3 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
GUSB	CES1	109245	10562416	Affinity Capture-Western
GUSB	CES1	107494	10562416	Affinity Capture-Western
CES1	CES1	107494	12679808	Co-crystal Structure

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:1 results

MGI ID: MGI:88378
Data Attributes: MGI curated