AutismKB 2.0

Annotation Details for POLQ


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Basic Information Top
Gene Symbol:POLQ ( DKFZp781A0112,POLH,PRO0327 )
Gene Full Name: polymerase (DNA directed), theta
Band: 3q13.33
Quick LinksEntrez ID:10721; OMIM: 604419; Uniprot ID:Q59EE4_HUMAN; ENSEMBL ID: ENSG00000051341; HGNC ID: 9186
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005694IEA-chromosome-
GO:0005737IBA-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003682IDA-chromatin binding25642963
GO:0003684TAS-damaged DNA binding10395804
GO:0003887IDA-DNA-directed DNA polymerase activity14576298
GO:0003887IMP-DNA-directed DNA polymerase activity22135286
GO:0005515IPI-protein binding25642963
GO:0005524IEA-ATP binding-
GO:0008409IBANOT5'-3' exonuclease activity-
GO:0043142IDA-single-stranded DNA-dependent ATPase activity14576298
GO:0051575IDA-5'-deoxyribose-5-phosphate lyase activity19188258
GO ID Evidence Qualifier GO_term References
GO:0000724TAS-double-strand break repair via homologous recombination-
GO:0006261IBA-DNA-dependent DNA replication-
GO:0006281TAS-DNA repair10395804
GO:0006284IDA-base-excision repair19188258
GO:0006302IDA-double-strand break repair22135286
GO:0006974IDA-cellular response to DNA damage stimulus25642963
GO:0016446ISS-somatic hypermutation of immunoglobulin genes-
GO:0051260IDA-protein homooligomerization25643323
GO:0071897IEA-DNA biosynthetic process-
GO:0097681IDA-double-strand break repair via alternative nonhomologous end joining25643323
GO:2000042IDA-negative regulation of double-strand break repair via homologous recombination25642963
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
POLQAP2S110758917353931 Affinity Capture-MS
POLQAP2S111594617353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2155399
  • Data Attributes: HomoloGene calculated
No data