Annotation Details for PLK4
Basic Information Top
| Gene Symbol: | PLK4 ( SAK,STK18 ) |
|---|---|
| Gene Full Name: | polo-like kinase 4 |
| Band: | 4q28.1 |
| Quick Links | Entrez ID:10733; OMIM: 605031; Uniprot ID:PLK4_HUMAN; ENSEMBL ID: ENSG00000142731; HGNC ID: 11397 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001741 | IEA | - | XY body | - |
| GO:0005730 | ISS | - | nucleolus | - |
| GO:0005813 | IDA | - | centrosome | 21399614 |
| GO:0005814 | IDA | - | centriole | 16244668 |
| GO:0005829 | IDA | - | cytosol | - |
| GO:0005829 | TAS | - | cytosol | - |
| GO:0032154 | IEA | - | cleavage furrow | - |
| GO:0098536 | ISS | - | deuterosome | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0004674 | IDA | - | protein serine/threonine kinase activity | 21725316 |
| GO:0004674 | ISS | - | protein serine/threonine kinase activity | - |
| GO:0005515 | IPI | - | protein binding | 16189514 |
| GO:0005524 | IEA | - | ATP binding | - |
| GO:0042802 | IPI | - | identical protein binding | 16189514 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000086 | TAS | - | G2/M transition of mitotic cell cycle | - |
| GO:0006468 | IEA | - | protein phosphorylation | - |
| GO:0007099 | IMP | - | centriole replication | 21725316 |
| GO:0046601 | IDA | - | positive regulation of centriole replication | 22349705 |
| GO:0046601 | IMP | - | positive regulation of centriole replication | 16244668 |
| GO:0060707 | ISS | - | trophoblast giant cell differentiation | - |
| GO:0097711 | TAS | - | ciliary basal body docking | - |
| GO:0098535 | ISS | - | de novo centriole assembly involved in multi-ciliated epithelial cell differentiation | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| PLK4 | SFN | 115956 | 16189514 | Affinity Capture-Western; Two-hybrid |
| PLK4 | SFN | 109072 | 16189514 | Affinity Capture-Western; Two-hybrid |
| PLK4 | PLK4 | 115956 | 16189514 | Two-hybrid |
| MTUS2 | PLK4 | 115956 | 16189514 | Two-hybrid |
| MTUS2 | PLK4 | 116880 | 16189514 | Two-hybrid |
| FAM46C | PLK4 | 115956 | 16189514 | Two-hybrid |
| FAM46C | PLK4 | 120205 | 16189514 | Two-hybrid |
| No data |
| No data |



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